posted at 4/3/2013 9:16 AM EDT
Have you looked at the CDC maps of malaria load? How high risk is the area you are traveling to? Also, is it malaria/mosquito season there? It's really hard to say, since this is about risk trade-offs, and the risks are hard to quantify. I think your arguments for skipping it are reasonable, but if you do, I would really avoid hanging out outdoors and make liberal use of a DEET-containing repellant.
I was in a similar quandry with a previous pregnancy, and was leaning towards foregoing the malaria prophylaxis, but then lost the pregnancy so it was a bit moot. Trip ended up falling during my 2ww, and I skipped the drugs anyway. Not sure this is really good advice though, and having 1 person say "I did this and didn't get malaria" really shouldn't be very persuasive in your decision making! Prior to TTC, I tended to just take the drugs...
Also, avoiding mosquitoes could be a good idea for other reasons even if you take the malaria pills--like if this is an area with dengue fever. ALso, the malaria prophylaxis I think doesn't reduce risk of infection to 0, just makes it lower than otherwise, if I recall correctly.
ETA: Also, wear long pants, long sleeves, socks--basically keeping your skin covered--can help reduce risk substantially as well. AND, if I had to put money on this, I'm guessing your OB will say to take them. I did have a friend contract malaria last year on a trip to Africa, and it was pretty crummy, so there is a counter-balancing anecodote to my own "I didn't take the pills and I didn't get malaria".