On Sunday afternoon, they did.

But thanks in large part to a monster effort in the middle from linebacker Brandon Spikes, New England left Ralph Wilson Stadium with a come-from-behind 52-28 win, improving its much-talked-about record to 2-2.

Spikes forced two fumbles, a tide-turning one on the goal line late in the first half, and another in the fourth quarter. Both were recovered by teammates.

His effort was part of a hard-hitting performance by the defense. It made some crushing hits — none better than Vince Wilfork’s clean but devastating takedown of receiver Donald Jones over the middle — and had four interceptions.

Devin McCourty, who had received the lion’s share of blame for the unit’s late-game breakdown in Baltimore a week earlier, had two of the picks.

It wasn’t perfect, with broken coverage on a 33-yard catch-and-run by Jones the most glaring mistake, bringing back memories of last year’s defense. The score gave Buffalo a 21-7 lead with four minutes gone in the third quarter.

But New England’s offense also got rolling, eschewing trick plays for what works: Tom Brady running the no-huddle, heaping doses of Wes Welker, getting the ball to Rob Gronkowski, and a new wrinkle: great running efforts from Stevan Ridley and rookie Brandon Bolden.

Ridley and Bolden each had more than 100 yards rushing, the first time the Patriots have had two running backs accomplish that in the same game since 1980. Welker and Gronkowski also both topped 100 yards receiving, part of a 340-yard passing performance for Brady, who was sacked just once.

It was just the second time in NFL history that a team has had two 100-yard rushers and two 100-yard receivers in the same game; Green Bay was the first, against the Lions in the 2008 regular-season finale.

New England got a sterling effort from its offensive line, which played without injured Logan Mankins against one of the top defensive tackle tandems in the NFL in Kyle Williams and Marcell Dareus.

“Kyle Williams is a beast in there; so is Dareus,” said the Patriots’ Donald Thomas, who stepped into Mankins’s spot at left guard. Of the rushing numbers, he said, “It feels great to do that and get those yards for those guys. It’s satisfying as an offensive line to have a day like that.”

Bills coach Chan Gailey didn’t hold back when asked about his defense’s performance against the run.

“To be honest with you, they whipped us. Bottom line, they whipped us,” Gailey said. “They blocked us, we did not get off blocks and get to the ball. They blocked us and we were making our corners make a bunch of tackles.”

He added that he did not expect the Patriots to run the ball like that “at all”.

Spikes, the third-year University of Florida product, had a solid game in the opener against Tennessee but then looked lackluster against Arizona and Baltimore. Colorful and at times controversial — he was the only Patriots player to really speak out about the replacement officials, sending an R-rated tweet late last Sunday night that the refs were needed back at Foot Locker, where workers wear black-and-white-striped jerseys.

“He’s a different character,” Rob Ninkovich said of Spikes, who did not talk after the game. “He has tons of energy. I love playing with the guy. I always know where he is because he’s always screaming at me to make plays.

“He has things you can’t teach – instincts.”

“He had a huge game,” Wilfork said. “He’s coming into his own and becoming an elite player. We need that from everyone.”